Postdoctoral Research Fellow - Hematopoietic Malignancies
Cincinnati Children's Hospital Medical Center
Location: Cincinnati, Ohio
Academic / Research
Internal Number: 138904
A Research Fellow position is immediately available in the lab of Dr. Timothy Chlon for a post-doctoral scientist with interest in hematopoietic stem cell biology and hematologic malignancy. The lab uses a combination of genetic mouse strains, human pluripotent stem cells, and cultured cell lines to study the mechanistic basis and potential therapeutic strategies for Acute Myeloid Leukemia and Myelodysplastic Syndrome (AML/MDS) in patients bearing mutations in DDX41, the most commonly mutated gene causing inherited predisposition to AML/MDS. The fellow will pursue genetic engineering studies in mice and/or human iPSC to model disease-relevant combinations of gene mutations and determine their effect on hematopoietic stem cell function.
MAJOR DUTIES AND RESPONSIBILITIES:
Design, execute, and record laboratory experiments, and analyze the data.
Research and improve current methods and evaluate innovative techniques. Implement this knowledge in the Division/Department.
Present research at laboratory meetings, journal clubs, seminars, and meetings.
Draft, write, and edit scientific reports, papers, journal articles, abstracts, and grants.
Maintain currency in field through continuing education, literature, and seminars.
Attend required Cincinnati Children's training sessions and ensure regulatory compliance with all policies and procedures.
Perform other duties as assigned.
Cincinnati Children's Research and Training at a Glance
Among the top in NIH funding for pediatric research institutions
Over 1.4 million square feet of research laboratory space
900+ scientists conducting basic, translational, and clinical research
Over 2000 publications annually in top-tier journals
Access to Employee Resource Groups and Mentorship programs
Postdocs have gone on to careers in academia, biotech, pharma, teaching etc.
Ph.D. in related discipline, MD, or equivalent required.
The ideal candidate will have cell and molecular biology lab skills, including cell culture, protein and nucleic acid isolation and analysis, and related lab methods. Bioinformatics expertise is a plus but is not required. Dr. Chlon is committed to the successful career development of trainees and will work with the fellow to achieve their career goals.
REQUIRED SKILLS: Excellent written, verbal, and interpersonal communication skills. Demonstrate attention to detail, strong organizational skills, supervisory ability, and an innovative approach to experimental design. Computer literate and working knowledge of software applications (word processing, spreadsheet, and database). Analytical ability sufficient to compare data; mathematical ability sufficient to perform algebraic calculations and statistical analysis. Ability to synthesize information and to create and deal with new situations by applying past experiences. Expressed willingness to teach others and share results. Capable of meeting time demands necessary to execute experiments.
Cincinnati Children's is proud to be an Equal Opportunity Employer that values and treasures Diversity, Equity, and Inclusion. We are committed to creating an environment of dignity and respect for all our employees, patients, and families (EEO/AA).
About Cincinnati Children's Hospital Medical Center
At Cincinnati Children’s, we come to work with one goal: to make children’s health better. We believe in a team approach, both in caring for patients and their families, and in advancing science and discovery. We strive to do better, and find energy and inspiration in our shared purpose. If you want to be the best you can be, you can do it at Cincinnati Children’s.